活動レポート

原著論文

Yamauchi, T., Yoshioka, M., Fukazawa, A., Mori, H., Nishizawa, N.K., Tsutsumi, N., Yoshioka, H. and Nakazono, M. (2017) An NADPH oxidase RBOH functions in rice roots during lysigenous aerenchyma formation under oxygen-deficient conditions. Plant Cell 29, 775-790.
 
Adachi, H., Ishihama, N., Nakano, T., Yoshioka, M. and Yoshioka, H. (2016) Nicotiana benthamiana MAPK-WRKY pathway confers resistance to a necrotrophic pathogen Botrytis cinerea. Plant Signal. Behav. 11(6), e1183085.
 
Ichimura, K., Shinzato, T., Edaki, M., Yoshioka, H. and Shirasu, K. (2016) SGT1 contributes to maintaining protein levels of MEK2DD to facilitate hypersensitive response-like cell death in Nicotiana benthamiana. Physiol. Mol. Plant Pathol. 94, 47-52.
 
Adachi, H., Nakano, T., Miyagawa, N., Ishihama, N., Yoshioka, M., Katou, Y., Yaeno, T., Shirasu, K. and Yoshioka, H. (2015) WRKY transcription factors phosphorylated by MAPK regulate a plant immune NADPH oxidase in Nicotiana benthamiana. Plant Cell 27, 2645-2663. [プレスリリース] [highlighted in Nature Plants]
 
Sugiyama, A., Fukuda, S., Takanashi, K., Yoshioka, M., Yoshioka, H., Narusaka, Y., Narusaka, M., Kojima, M., Sakakibara, H., Shitan, N., Sato, S., Tabata, S., Kawaguchi, M. and Yazaki, K. (2015) Molecular characterization of LjABCG1, an ATP-binding cassette protein in Lotus japonicus. PLoS ONE 10, e0139127.
 
Nakano, M., Yoshioka, H., Ohnishi, K., Hikichi, Y. and Kiba, A. (2015) Cell death-inducing stresses are required for defense activation in DS1-phosphatidic acid phosphatase-silenced Nicotiana benthamiana. J. Plant Physiol. 184, 15-19.
 
Le Roux, C., Huet, G., Jauneau, A., Camborde, L., Tremousaygue, D., Kraut, A., Zhou, B., Levaillant, M., Adachi, H., Yoshioka, H., Raffaele, S., Berthome, R., Coute, Y., Parker, J.E. and Deslandes, L. (2015) A receptor pair with an integrated decoy converts pathogen disabling of transcription factors to immunity. Cell 161, 1074-1088. [highlighted in Nature Reviews Immunology]
 
Tamura, Y., Hattori, M., Yoshioka, H., Yoshioka, M., Takahashi, A., Wu, J., Sentoku, N. and Yasui, H. (2014) Map-based cloning and characterization of a brown planthopper resistance gene BPH26 from Oryza sativa L. ssp. indicacultivar ADR52. Sci. Rep. 4, 5872. [プレスリリース]
 
Kiba, A., Galis, I., Hojo, Y., Ohnishi, K., Yoshioka, H. and Hikichi, Y. (2014) SEC14 phospholipid transfer protein is involved in lipid signaling-mediated plant immune responses in Nicotiana benthamiana. PLoS ONE 9, e98150. 
 
Nakano, M., Nishihara, M., Yoshioka, H., Ohnishi, K., Hikichi, Y. and Kiba, A.(2014) Silencing of DS2 aminoacylase-like genes confirms basal resistance to Phytophthora infestans in Nicotiana benthamiana. Plant Signal. Behav. 9, e28004. 
 
Nakano, M., Nishihara, M., Yoshioka, H., Takahashi, H., Sawasaki, T., Ohnishi, K., Hikichi, Y. and Kiba, A. (2013) Suppression of DS1 phosphatidic acid phosphatase confirms resistance to Ralstonia solanacearum in Nicotiana benthamiana. PLoS ONE 8, e75124. 
 
Gupta, M., Yoshioka, H., Ohnishi, K., Mizumoto, H., Hikichi, Y. and Kiba, A.(2013) A translationally controlled tumor protein negatively regulates the hypersensitive response in Nicotiana benthamiana. Plant Cell Physiol. 54, 1403-1414.
 
Mase, K., Ishihama, N., Mori, H., Takahashi, H., Kaminaka, H., Kodama, M. and Yoshioka, H. (2013) Ethylene responsive AP2/ERF transcription factor MACD1 participates in phytotoxin-triggered programmed cell death. Mol. Plant-Microbe Interact. 26, 868-879.
 
Asai, S., Ichikawa, T., Nomura, H., Kobayashi, M., Kamiyoshihara, Y., Mori, H., Kadota, Y., Zipfel, C., Jones, J.D.G. and Yoshioka, H. (2013) The variable domain of a plant calcium-dependent protein kinase (CDPK) confers subcellular localization and substrate recognition for NADPH oxidase. J. Biol. Chem. 288, 14332-14340.
 
Yamaguchi, K., Yamada, K., Ishikawa, K., Yoshimura, S., Hayashi, N., Uchihashi, K., Ishihama, N., Kishi-Kaboshi, M., Takahashi, A., Tsuge, S., Ochiai, H., Tada, Y., Shimamoto, K., Yoshioka, H. and Kawasaki, T. (2013) A receptor-like cytoplasmic kinase targeted by a plant pathogen effector is directly phosphorylated by the chitin receptor and mediates rice immunity. Cell Host Microbe 13, 347-357.
 
Kobayashi, M., Yoshioka, M., Asai, S., Nomura, H., Kuchimura, K., Mori, H., Doke, N. and Yoshioka, H. (2012) StCDPK5 confers resistance to late blight pathogen but increases susceptibility to early blight pathogen in potato via reactive oxygen species burst. New Phytol. 196, 223-237. [communicated in Mair, A. and Teige, M. (2012) Shaping the pathogen response by protein kinase triggered oxidative burst. New Phytol. 196, 4-6.]
 
Komori, D., Nishihara, M., Takahashi, A., Gupta, M., Yoshioka, H., Mizumoto, H., Ohnishi, K., Hikichi, Y. and Kiba, A. (2012) Isolation and characterization of an asparagine-rich protein that regulates hypersensitive cell death-mediated resistance in Nicotiana plants. Plant Biotechnol. 29, 293-300.
 
Mase, K., Mizuno, T., Ishihama, N., Fujii, T., Mori, H., Kodama, M. and Yoshioka, H. (2012) Ethylene signaling pathway and MAPK cascades are required for AAL toxin-induced programmed cell death. Mol. Plant-Microbe Interact. 25, 1015-1025.
 
Nomura, H., Komori, T., Uemura, S., Kanda, Y., Shimotani, K., Nakai, K., Furuichi, T., Takebayashi, K., Sugimoto, T., Sano, S., Suwastika, I.N., Fukusaki, E., Yoshioka, H., Nakahira, Y. and Shiina, T. (2012) Chloroplast-mediated activation of plant immune signalling in Arabidopsis. Nature Commun. 3, 926.
 
Kiba, A., Nakano, M., Vincent-Pope, P., Takahashi, H., Sawasaki, T., Endo, Y., Ohnishi, K., Yoshioka, H. and Hikichi, Y. (2012) A novel Sec14 phospholipid transfer protein from Nicotiana benthamiana is up-regulated in response to Ralstonia solanacearum infection, pathogen associated molecular patterns and effector molecules and involved in plant immunity. J. Plant Physiol. 169, 1017-1022.
 
Yoshino, K., Irieda, H., Sugimoto, F., Yoshioka, H., Okuno, T. and Takano, Y.(2012) Cell death of Nicotiana benthamiana is induced by secreted protein NIS1 of Colletotrichum orbiculare and is suppressed by a homologue of CgDN3. Mol. Plant-Microbe Interact. 25, 625-636.
 
Ishihama, N., Yamada, R., Yoshioka, M., Katou, S. and Yoshioka, H. (2011) Phosphorylation of the Nicotiana benthamiana WRKY8 transcription factor by MAPK functions in the defense response. Plant Cell 23, 1153-1170. [プレスリリース]
 
Asai, S., Yoshioka, M., Nomura, H., Tone, C., Nakajima, K., Nakane, E., Doke, N. and Yoshioka, H. (2011) A plastidic glucose-6-phosphate dehydrogenase is responsible for hypersensitive response cell death and reactive oxygen species production. J. Gen. Plant Pathol. 77, 152-162.
 
Nagamangala Kanchiswamy, C., Maffei, M.E., Yoshioka, H., Sawasaki, T. and Arimura, G. (2010) Ca2+-dependent protein kinases and their substrate HsfB2a are differently involved in the heat response signaling pathway in Arabidopsis. Plant Biotechnol. 27, 469-473.
 
Kobayashi, M., Ishihama, N., Yoshioka, H., Takabatake, R., Tsuda S., Seo, S., Ohashi, Y. and Mitsuhara, I. (2010) Analyses of the cis-regulatory regions responsible for the transcriptional activation of the N resistance gene by Tobacco mosaic virus. J. Phytopathol. 158, 826-828.
 
Nagamangala Kanchiswamy, C., Takahashi, H., Quadro, S., Maffei, M.E., Bossi, S., Bertea, C., Zebelo, S.A., Muroi, A., Ishihama, N., Yoshioka, H., Boland, W., Takabayashi, J., Endo, Y., Sawasaki, T. and Arimura, G. (2010) Regulation of Arabidopsis defense responses against Spodoptera littoralis by CPK-mediated calcium signaling. BMC Plant Biol. 10, 97.
 
Asai, S., Mase, K. and Yoshioka, H. (2010) A key enzyme for flavin synthesis is required for nitric oxide and reactive oxygen species production in disease resistance. Plant J. 62, 911-924.
 
Maimbo, M., Ohnishi, K., Hikichi, Y., Yoshioka, H. and Kiba, A. (2010) S-glycoprotein-like protein regulates defense responses in Nicotiana plants against Ralstonia solanacearum. Plant Physiol. 152, 2023-2035.
 
Tanaka, S., Ishihama, N., Yoshioka, H., Huser, A., O'Connell, R., Tsuji, G., Tsuge, S. and Kubo, Y. (2009) The Colletotrichum orbiculare ssd1 mutant enhances Nicotiana benthamiana basal resistance by activating a mitogen-activated protein kinase pathway. Plant Cell 21, 2517-2526.
 
Ohde, T., Matsumoto, M., Morita-Miwa, M., Matsuura, H., Yoshioka, H., Yaginuma, T. and Niimi, T. (2009) Vestigial and scalloped in the ladybird beetle: a conserved function in wing development and a novel function in pupal ecdysis. Insect Mol. Biol. 18, 571-581.
 
Asai, S. and Yoshioka, H. (2009) Nitric oxide as a partner of reactive oxygen species participates in disease resistance to necrotrophic pathogen Botrytis cinerea in Nicotiana benthamiana. Mol. Plant-Microbe Interact. 22, 619-629.
 
Kawamura, Y., Hase, S., Takenaka, S., Kanayama, Y., Yoshioka, H., Kamoun, S. and Takahashi, H. (2009) INF1 elicitin activates jasmonic acid- and ethylene-mediated signalling pathways and induces resistance to bacterial wilt disease in tomato. J. Phytopathol. 157, 287-297.
 
Asai, S., Ohta, K. and Yoshioka, H. (2008) MAPK signaling regulates nitric oxide and NADPH oxidase-dependent oxidative bursts in Nicotiana benthamiana. Plant Cell 20, 1390-1406. [プレスリリース]
 
Kato, H., Asai, S., Yamamoto-Katou, A., Yoshioka, H., Doke, N. and Kawakita, K. (2008) Involvement of NbNOA1 in NO production and defense responses in INF1-treated Nicotiana benthamiana. J. Gen. Plant Pathol. 74, 15-23.
 
Wong, H.L., Pinontoan, R., Hayashi, K., Tabata, R., Yaeno, T., Hasegawa, K., Kojima, C., Yoshioka, H., Iba, K., Kawasaki, T. and Shimamoto, K. (2007) Regulation of rice NADPH oxidase by binding of Rac GTPase to its N-terminal extension. Plant Cell 19, 4022-4034.
 
Maimbo, M., Ohnishi, K., Hikichi, Y., Yoshioka, H. and Kiba, A. (2007) Induction of a small heat shock protein and its functional roles in Nicotiana plants in the defense response against Ralstonia solanacearum. Plant Physiol. 145, 1588-1599.
 
Kobayashi, M., Ohura, I., Kawakita, K., Yokota, N., Fujiwara, M., Shimamoto, K., Doke, N. and Yoshioka, H. (2007) Calcium-dependent protein kinases regulate the production of reactive oxygen species by potato NADPH oxidase. Plant Cell 19, 1065-1080.
 
Yamamoto-Katou, A., Katou, S., Yoshioka, H., Doke, N. and Kawakita, K.(2006) Nitrate reductase is responsible for elicitin-induced nitric oxide production in Nicotiana benthamiana. Plant Cell Physiol.  47, 726-735.
 
Saito, S., Yamamoto-Katou, A., Yoshioka, H., Doke, N. and Kawakita, K. (2006) Peroxynitrite generation and tyrosine nitration in defense responses in tobacco BY-2 cells. Plant Cell Physiol.  47, 689-697.
 
Yang, C.-W., Gonzalez-Lamothe, R., Ewan, R.A., Rowland, O., Yoshioka, H., Shenton, M., Ye, H., O'Donnell, E., Jones, J.D.G. and Sadanandom, A. (2006) The E3 ubiquitin ligase activity of Arabidopsis PLANT U-BOX17 and its functional tobacco homolog ACRE276 are required for cell death and defense.Plant Cell 18, 1084-1098.
 
Kobayashi, M., Kawakita, K., Maeshima, M., Doke, N. and Yoshioka, H. (2006) Subcellular localization of Strboh proteins and NADPH-dependent O2--generating activity in potato tuber tissues. J. Exp. Bot. 57, 1373-1379.
 
Kobae, Y., Sekino, T., Yoshioka, H., Nakagawa, T., Martinoia, E. and Maeshima, M. (2006) Loss of AtPDR8, a plasma membrane ABC transporter of Arabidopsis thaliana, causes hypersensitive cell death upon pathogen infection. Plant Cell Physiol. 47, 309-318.
 
Yamamizo, C., Kuchimura, K., Kobayashi, A., Katou, S., Kawakita, K., Jones, J.D.G., Doke, N. and Yoshioka, H. (2006) Rewiring mitogen-activated protein kinase cascade by positive feedback confers potato blight resistance. Plant Physiol. 140: 681-692.
 
Katou, S., Yoshioka, H., Kawakita, K., Rowland, O., Jones, J.D.G., Mori, H. and Doke, N. (2005) Involvement of PPS3 phosphorylated by elicitor-responsive mitogen-activated protein kinases in the regulation of plant cell death. Plant Physiol. 139, 1914-1926.
 
Morita-Yamamuro, C., Tsutsui, T., Sato, M., Yoshioka, H., Tamaoki, M., Ogawa, D. Matsuura, H., Yoshihara, T., Ikeda, A., Uyeda, I. and Yamaguchi, J. (2005) The Arabidopsis gene CAD1 controls programmed cell death in the plant immune system and encodes a protein containing a MACPF domain. Plant Cell Physiol. 46, 902-912.
 
Rowland, O., Ludwig, A.A., Merrick, C.J., Baillieul, F., Tracy, F.E., Durrant, W.E., Fritz-Laylin, L., Nekrasov, V., Sjoander, K., Yoshioka, H. and Jones, J.D.G.(2005) Functional analysis of Avr9/Cf-9 rapidly elicited genes identifies a protein kinase, ACIK1, that is essential for full Cf-9-dependent disease resistance in tomato. Plant Cell 17, 295-310.
 
Rivas, S., Rougon-Cardoso, A., Smoker, M., Schauser, L., Yoshioka, H. and Jones, J.D.G. (2004) CITRX thioredoxin interacts with the tomato Cf-9 resistance protein and negatively regulates defence. EMBO J. 23, 2156-2165.
 
Yamamoto, A., Katou, S., Yoshioka, H., Doke, N. and Kawakita, K. (2004) Involvement of nitric oxide generation in hypersensitive cell death induced by elicitin in tobacco cell suspension culture. J. Gen. Plant Pathol. 70, 85-92.
Nakane, E., Kawakita, K., Doke, N. and Yoshioka, H. (2003) Elicitation of primary and secondary metabolism during defense in the potato. J. Gen. Plant Pathol. 69, 378-384.
 
Kanzaki, H., Saitoh, H., Ito, A., Fujisawa, S., Kamoun, S., Katou, S., Yoshioka, H. and Terauchi, R. (2003) Cytosolic HSP90 and HSP70 are essential components of INF1-mediated hypersensitive response and non-host resistance to Pseudomonas cichorii in Nicotiana benthamiana. Mol. Plant Pathol. 4, 383-391.
 
Yamamoto, A., Katou, S., Yoshioka, H., Doke, N. and Kawakita, K. (2003) Nitrate reductase, a nitric oxide-producing enzyme: induction by pathogen signals. J. Gen. Plant Pathol. 69, 218-229.
Takemoto, D., Yoshioka, H., Doke, N. and Kawakita, K. (2003) Disease stress-inducible genes of tobacco: expression profile of elicitor-responsive genes isolated by substractive hybridization. Physiol. Plant. 118, 545-553.
 
Katou, S., Yamamoto, A., Yoshioka. H., Kawakita, K. and Doke, N. (2003) Functional analysis of potato mitogen-activated protein kinase kinase, StMEK1. J. Gen. Plant Pathol. 69, 161-168.
 
Yoshioka, H., Numata, N., Nakajima, K., Katou, S., Kawakita, K., Rowland, O., Jones, J.D.G. and Doke, N. (2003) Nicotiana benthamiana gp91phox homologs NbrbohA and NbrbohB participate in H2O2 accumulation and resistance to Phytophthora infestans. Plant Cell 15, 706-718.
 
Yoshioka, H., Sugie, K., Park, H.-J., Maeda, H., Tsuda, N., Kawakita, K. and Doke, N. (2001) Induction of plant gp91phox homolog by fungal cell wall, arachidonic acid and salicylic acid in potato. Mol. Plant-Microbe Interact.14, 725-736.
 
Katou, S., Senda, K., Yoshioka, H., Doke, N. and Kawakita, K. (1999) A 51 kDa protein kinase of potato activated with hyphal wall components from Phytophthora infestans. Plant Cell Physiol. 40, 825-831.
 
Miura, Y., Yoshioka, H., Park, H.-J., Kawakita, K. and Doke, N. (1999) Plasma membarne perturbation in association with calcium ion movement followed by fungal elicitor-stimulated oxidative burst and defense gene activation in potato tuber. Ann. Phytopathol. Soc. Jpn 65, 447-453.
 
Takemoto, D., Maeda, H., Yoshioka, H., Doke, N. and Kawakita, K. (1999) Effect of cytochalasin D on defense responses of potato tuber discs treated with hyphal wall components of Phytophthora infestans. Plant Sci. 141, 219-226.
 
Trepp, G., van de Mortel, M., Yoshioka, H., Miller, S.S., Samac, D.A., Gantt, J.S. and Vance, C.P. (1999) NADH-glutamate synthase in alfalfa root nodules: genetic regulation and cellular expression. Plant Physiol. 119, 817-828.
 
Yoshioka, H., Gregerson, R.G., Samac, D.A., Hoevens, K.C.M., Trepp, G., Gantt, J.S. and Vance, C.P. (1999) Aspartate aminotransferase in alfalfa nodules: Localization of mRNA during effective and ineffective nodules development and promoter analysis. Mol. Plant-Microbe Interact. 12, 263-274.
 
Yoshioka, H., Yamada, N. and Doke, N. (1999) cDNA cloning of sesquiterpene cyclase and squalene synthase, and expression of the genes in potato tuber infected with Phytophthora infestans. Plant Cell Physiol. 40, 993-998.
 
Park, H.-J., Miura, Y., Kawakita, K., Yoshioka, H. and Doke, N. (1998) Physiological mechanisms of a sub-systemic oxidative burst triggered by elicitor-induced local oxidative burst in potato tuber slices. Plant Cell Physiol.39, 1218-1225.
 
Pathirana, S.M., Samac, D.A., Roeven, R., Yoshioka, H., Vance, C.P. and Gantt, J.S. (1997) Analyses of phosphoenolpyruvate carboxylase gene structure and expression in alfalfa nodules. Plant J. 12, 293-304.
 
Shi, L., Twary, S.N., Yoshioka, H., Gregerson, R.G., Miller, S.S., Samac, D.A., Gantt, J.S., Unkefer, P.J. and Vance, C.P. (1997) Nitrogen assimilation in alfalfa: Isolation and characterization of an asparagine synthetase gene showing enhanced expression in root nodules and dark-adapted leaves. Plant Cell 9, 1339-1356.