We study the genome, its associated epigenomes, and their dynamics
during development and during evolution.
Genome and epigenome evolution through retrotransposons in mammals is a major interest.

What's new

2022/09/22
Our paper on the epigenome evolution using human and chimpanzee iPS cells has been accepted by Molecular Biology and Evolution.
Hirata et al. "Sequence divergence and retrotransposon insertion underlie interspecific epigenetic differences in primates."
2022/09/18
Ichiyanagi presented an invited talk in the workshop entitled “Stem cell technologies driving cellular anthropology and primatology” in the joint annual meeting of the Antoropological Society of Nippon and Primate Society of Japan.
Title: Toward the understanding of the epigenome evolution in primates.
2022/09/15
Ichiyanagi organized a workshop entitled “the basis and function of the higher order nuclear structure” in the 94th annual meeting of Japanese Society of Genetics.
2022/09/15
Otsuka (M. Sc. student), Kawase (Ph. D. student), and Ichiyanagi presented a talk in the 94th annual meeting of Japanese Society of Genetics.
Otsuka: Alteration in DNA methylome and transcriptome during spermatogenesis in diabetic mice.
Kawase: Loss of H3K9me3 due to SETDB1 deficiency in mouse male germ cells derepress ERVK retrotransposons.
Ichiyanagi: Genomic origins of interspecies epigenetic differences in human and chimpanzee iPS cells.
2022/09/14
Kawase organized (Ph. D. student) the 1st meeting of young researchers of Japanese Society of Genetics.
2022/06/18
Ichiyanagi presented an invited talk in the symposium for enviromental epigenomics.
Title: Epigenetic regulation of retrotransposons in mammals.
2022/04/26
Our paper on the expression dynamics of piRNAs during male germ cell development has been accepted by Frontiers in Cell and Developmental Biology.
Kawase M. and Ichiyanagi K. "The expression dynamics of piRNAs derived from male germline piRNA clusters and retrotransposons."
link to the article page
2022/04/01
Ms. Yoshida and Mr. Suzuki (MSc. students) joined the lab.
2022/03/23
Ichiyanagi presented an invited talk in the 50th hominization research meeting.
Title: Comparative study on the epigenomes of human and chimpazee iPS cells.
2022/03/18
Ichiyanagi presented an invited talk in a symposium entitled "Medical biosciences using primate iPS cells" in the annual meeting of Japanease Society of Regenerative Medicine.
Title: Study on the epigenome evolution using primate iPS cells.
2022/01/14
Meeting Report on the 5th TE meeting has been published in Mobile DNA. [link]
2021/12/03
Ichiyanagi organized a workshop entitled "Epigenetic regulation of retrotransposons in germ cells and its transgenerational effects" in the annual meeting of Japanese Society of Molecular Biology, and Masaki Kawase (Ph. D. student) presented an invited talk there.
Title: Role for H3K9me3 and DNA methylation in regulation of retrotransposons in mouse spermatocytes.
2021/12/02
Ichiyanagi presented an invited talk in a workshop entitled "Genome functions created by transposable elements" in the annual meeting of Japanese Society of Molecular Biology.
Title: Mouse B2 SINE serves as a transposable chromatin boundary.
  • Nagoya University
  • Graduate School of Bioagricultural Sciences and School of Agricultural Sciences, Nagoya University