We study the genome, its associated epigenomes, and their dynamics
during development and during evolution.
Genome and epigenome evolution through retrotransposons in mammals is a major interest.

What's new (Laboratory of Genome and Epigenome Dynamics, Nagoya University)

Sophia Nunez and Jacob Baker (3rd year undergraduates in North Carolina State University) joind the lab as short-tem students
Our paper on the effect of insertions of mouse L1 retrotransposons on histone acetylation has been accepted by Mobile DNA.
Boyboy and Ichiyanagi "Insertion of short L1 sequences generates inter-strain histone acetylation differences in the mouse."
Buno and Pan (new Ph. D. students) joined the lab.
Kitao (post-doc) and Suzuki (M. Sc. student) presented a talk in the 4th spring meeting of Japanease Society of Genetics.
Kitao: The birth and evolution of species-specific genes - a transposon perspective.
Suzuki: Comparative study of transcriptome and chromatin accessibility in human and chimpanzee cells during neural development.
Meeting report for the 6th TE meeting has been published in Mobile DNA.
link to the article
Ichiyanagi presented a talk in a symposium entitled "The TE code in the formation of 3D nuclear structure" in the 46th annual meeting of Japanese Society of Molecular Biology.
Title: Regulatory mechanism of the expression of human Alu SINE.
Ms. Kawabe and Mr. Yamanaka joined the lab.
Our review article has been accepted by Genes and Genetic Systems.
Kawase and Ichiyanagi "Mouse retrotransposons: sequence structure, evolutional age, genomic distribution, and function." link to the article
Shimomuku´╝łM. Sc. student) received Young Best Poster Award in the 95th Annual Meeting of Japanese Society of Genetics.
Shimomuku and Yoshida (M. Sc. students) presented a poster in the 95th Annual Meeting of Japanese Society of Genetics.
Shimomuku: Mechanisms for regulation of retrotransposons in mouse male germ cells.
Yoshida: Analysis of chimeric transcripts composed of a gene and a retrotransposon induced in human COVID-19 patients.
Ichiyanagi gave an oral presentation in the 95th Annual Meeting of Japanese Society of Genetics.
Title: Analysis of expression of human Alu SINEs by the melRNA-seq method.
Suzuki (M. Sc. student) gave an invited talk in a symposium "EvoDevo studies of phenotypic novelty and diversity in mammals using zoo iPS cells" in the 74th Annual Meeting of the Zoological Society of Japan.
Title: Understanding primate evolution in view of epigenome using the iPSC-based technology.
Ishikawa (M. Sc. student) gave an oral presentation in the 74th Annual Meeting of the Zoological Society of Japan.
Title: Exploration of genes involved in a phenomenon of male-specific chromosome inactivation in the Japanese mealybug Planococcus kraunhiae
Ichiyanagi organized the 6th Japanease transposable element meeting in National Institute of Genetics; and Kitao (post-doc) and Ichiyanagi presented invited talks.
Kitao: Diversity of transposon-derived genes in amniotes.
Ichiyanagi: Regulatory mechanisms of SINE expression in mammals.
Suzuki (M. Sc. student) presented a poster in the 39th annual meeting of Primate Society of Japan.
Title: Comparative analysis of epigenomes between human and chimpanzee during their neural development.
Ichiyanagi presented an invited talk in the 16th annual meeting of Japanese Society of Epigenetics.
Title: Epigenetic regulation of retrotransposons during germ-cell development in the mouse --- a retrotransposon perspective.
Boyboy (Ph. D. student) presented a poster in the 36th International Mammalian Genome Conference.
Title: Paternal transgenerational epigenetic inheritance of diabetes in mice.
Kawase (Ph. D. student) and Ishikawa (M. Sc. student) presented a poster in the 3rd spring meeting of Japanease society of Genetics.
Kawase: The mechanisms of retrotransposon regulation in mouse spermatocytes by H3K9me3 and DNA methylation.
Ishikawa: Toward idemntifying genes involved in male-specific whole-chromosome silencing in a mealybug, Planococcus kraunhiae/.
  • Nagoya University
  • Graduate School of Bioagricultural Sciences and School of Agricultural Sciences, Nagoya University