Publications (96-127)
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127.
Watanabe, S.; Nishikawa, T.; Nakazaki, A. Total Synthesis of the Cardiotonic Steroid (+)-Cannogenol. J. Org. Chem., 2021, 86, 3605-3614. DOI: 10.1021/acs.joc.0c02966
126.
Uenoyama, R.; Miyazaki, T.; Hurst, J.; Beynon, R.; Asachi, M.; Murooka, T.; Onoda, I.; Miyazawa, Y.; Katayama, T.; Yamashita, T.; Kaneko, S.; Nishikawa, T.; Miyazaki, M. The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes. Sci. Adv., 2021, 7. DOI: 10.1126/sciadv.abd9135
125.
Suo, R.; Kashitani, M.; Oyama, H.; Adachi, M.; Nakahigashi, R.; Sakakibara, R.; Nishikawa, T.; Sugita, H.; Itoi, S. First Detection of Tetrodotoxins in the Cotylean Flatworm. Prosthiostomum trilineatum, Marine Drugs., 2021, 19, 40. DOI: 10.3390/md19010040
124.
Araki, Y.; Nakazaki, A.; Nishikawa, T. Biomimetic Synthesis of the CDE Ring Moiety of Physalins, Complex 13,14-Secosteroids. Org. Lett., 2021, 23, 989-994. DOI: 10.1021/acs.orglett.0c04198
123.
Jiang, Y.; Ozaki, T.; Harada, M.; Miyasaka, T.; Sato, H.; Miyamoto, K.; Kanazawa, J.; Liu, C.; Maruyama, J.; Adachi, M.; Nakazaki, A.; Nishikawa, T.; Uchiyama, M.; Minami, A.; Oikawa, H. Biosynthesis of Indole Diterpene Lolitrems: Radical-Induced Cyclization of an Epoxyalcohol Affording a Characteristic Lolitremane Skeleton. Angew. Chem. Int. Ed. , 2020, 59, 17996-18002. DOI: 10.1002/anie.202007280
122.
Nakane, Y.; Nakazaki, A.; Nishikawa, T. Studies toward the synthesis of chartelline C. J. Org. Chem. , 2020, 85, 7534-7542. DOI: 10.1021/acs.joc.0c00643
121.
Sasatsuki, H.; Nakazaki, A.; Uchida, K.; Shibata, T. Quantitative analysis of oxidized vitamin B1 metabolites generated by hypochlorous acid. Free Radic. Biol. Med. , 2020, 152, 197-206. DOI: 10.1016/j.freeradbiomed.2020.03.010
120.
Niki, M.; Hirata, Y.; Nakazaki, A.; Wu, J.; Kawagishi, H.; Nishikawa, T. Biomimetic Synthesis of Chaxine and its Related Compounds. J. Org. Chem. , 2020, 85, 4848-4860. DOI: 10.1021/acs.joc.9b03482
119.
Ono, Y.; Nakazaki, A.; Ueki, K.; Higuchi, K.; Sriphana, U.; Adachi, M.; Nishikawa, T. Asymmetric Synthesis of the Aromatic Fragment of Sespendole. J. Org. Chem. , 2019, 15, 9750-9757. DOI: 10.1021/acs.joc.9b01597
118.
Ushida, N.; Nagai, N.; Adachi, M.; Nishikawa, T. Concise Stereocontrolled Synthesis of an α -Carbagalactose Segment of RCAI-56, a Candidate Anticancer Agent. Synlett , 2019, 30, 977-981. DOI: 10.1055/s-0037-1611806
117.
Watanabe, S.; Nishikawa, T.; Nakazaki, A. Synthesis of Oxy-Functionalized Steroidal Skeletons via Mizoroki−Heck and Intramolecular Diels−Alder Reactions. Org. Lett., 2019, 21, 7410-7414. DOI: 10.1021/acs.orglett.9b02716
116.
Adachi, M.; Miyasaka, T.; Kudo, Y.; Sugimoto, K.; Yotsu-Yamashita, M.; Nishikawa, T. Total Syntheses and Determination of Absolute Configurations of Cep-212 and Cep-210, Predicted Biosynthetic Intermediates of Tetrodotoxin Isolated from Toxic Newt. Org. Lett., 2019, 21, 780-784. DOI: 10.1021/acs.orglett.8b04043
115.
Ito, S.; Yamamoto, Y.; Nishikawa, T. A concise synthesis of peramine, a metabolite of endophytic fungi. Biosci. Biotechnol. Biochem., 2018, 82, 2053-2058. DOI: 10.1080/09168451.2018.1511966
114.
Damnjanovic, J.; Matsunaga, N.; Adachi, M.; Nakano, H.; Iwasaki, Y. Facile Enzymatic Synthesis of Phosphatidylthreonine Using an Engineered Phospholipase D. Eur. J. Lipid Sci. Technol., 2018, 120, 1800089-1800095. DOI: 10.1002/ejlt.201800089
113.
Qi, J.; Cheng, L.; Sun, Y.; Hirata, Y.; Ushida, N.; Ma, Z.; Osada, H.; Nishikawa, T.; Xiang. L. Identification of an Asexual Reproduction Inducer of Phytopathogenic and Toxigenic Fusarium. Angew. Chem. Int. Ed., 2018, 57, 8100-8104. DOI: 10.1002/anie.201803329
112.
Huang, Y.; Nishikawa, T.; Nakazaki, A. Toward a synthesis of fawcettimine-type Lycopodium alkaloids: stereocontrolled synthesis of a functionalized azaspirocycle precursor. J. Org. Chem., 2018, 83, 11108-11117. DOI: 10.1021/acs.joc.8b01719
111.
Bian, L.; Cao, S.; Cheng, L.; Nakazaki, A.; Nishikawa, T.; Qi, J. Semi-synthesis and Structure-Activity Relationship of Neuritogenic Oleanene Derivatives.ChemMedChem, 2018, 13, 1972-1977. DOI: 10.1002/cmdc.201800352
110.
Nokura, Y.; Nakazaki, A.; Nishikawa, T. Synthesis of Dibromo Compounds Containing 2,6-Dioxabicyclo[3.1.1]heptane Similar to Core Moiety of Thromboxane A2. Heterocycles, 2018, 96, 127-136. DOI: 10.3987/COM-17-13814
109.
Yamamoto, Y.; Nakazaki, A.; Nishikawa, T. New regiocontrolled syntheses of pyrrolopyrazinones and its application to the synthesis of peramine. Tetrahedron. 2017, 73, 3443–3451. DOI: 10.1016/jet.2017.05.004
108.
Matsumoto, N.; Nakazaki, A.; Nishikawa, T. Concise synthesis of a cyclopentane intermediate possessing all nitrogen functionalities for pactamycin. Synlett, 2017, 2303-2306. DOI: 10.1055/s-0036-1588495
107.
Nakazaki, A.; Hashimoto, K.; Ikeda, A.; Shibata, T.; Nishikawa, T. De Novo Synthesis of Possible Candidates for the Inagami-Tamura Endogenous Digitalis-like Factor. J. Org. Chem. 2017, 82, 9097-9111. DOI: 10.1021/acs.joc.7b01640
106.
Nokura, Y.; Araki, Y.; Nakazaki, A.; Nishikawa, T. Synthetic Route to Oscillatoxin D and Its Analogues. Org. Lett, 19, 5992-5995, 2017. DOI: 10.1021/acs.orglett.7b03032
105.
Tsukamoto, T.; Chiba, Y.; Wakamori, M.; Yamada, T.; Tsunogae, S.; Cho, Y.; Sakakibara, R.; Imazu, T.; Tokoro, S.; Satake, Y.; Adachi, M.; Nishikawa, T.; Yotsu-Yamashita, M.; Konoki, K. Differential Binding of Tetrodotoxin and its Derivatives to Voltage-sensitive Sodium Channel Subtypes (Nav1.1 to Nav1.7) Br. J. Pharmacol, 174, 3881-3892, 2017. DOI: 10.1111/bph.13985
104.
Adachi, M.; Miyasaka, T.; Hashimoto, H.; Nishikawa, T. One-step Transformation of Trichloroacetamide into Isonitrile. Org. Lett, 19. 380-383, 2017. DOI: 10.1021/acs.orglett.6b03583
103.
Tsukamoto, T.; Chiba, Y.; Nakazaki, A.; Ishikawa, Y.; Nakane, Y.; Cho, Y.; Nishikawa, T.; Yotsu-Yamashita, M.; Wakamori, M.; Konoki, K. Inhibition of veratridine-induced delayed inactivation of the voltage-sensitive sodium channel by synthetic analogs of crambescin B, Bioorg. Med. Chem. Lett , 27, 1247-1251, 2017. DOI: 10.1016/j.bmcl.2017.01.054
102.
Hirata, Y.; Nakazaki, A.; Kawagishi, H.; Nishikawa, T. Biomimetic Synthesis and Structural Revision of Chaxine B and its Analogues, Org. Lett, 19,560-563, 2017, DOI: 10.1021/acs.orglett.6b03724
101.
Huang, W.-Y.; Nishikawa, T.; Nakazaki, A. Palladium-Catalyzed Cascade Wacker/Allylation Sequence with Allylic Alcohols Leading to Allylated Dihydropyrones, ACS Omega, 6, 487-495, 2017. DOI: 10.1021/acsomega.7b00028
100.
Kanie, S.; Nishikawa, T.; Ojika, M.; Oba, Y. One-pot Non-enzymatic Formation of Firefly Luciferin in a Neutral Buffer from p-Benzoquinone and Cysteine, Sci. Rep. 6, article number: 24794, 2016. DOI: 10.1038/srep24794
99.
Nakazaki, A.; Nakane, Y.; Ishikawa, Y.; Yotsu-Yamashita, M.; Nishikawa, T. Synthesis of Crambescin A–C Carboxylic Acids and Their Inhibitory Activity on Voltage-Gated Sodium Channels, Org. Biomol. Chem, 14, 5304-5309, 2016. DOI: 10.1039/C6OB00914J
98.
Adachi, M.; Miyazawa, Y; Nishikawa, T. Improved Syntheses of (+)-Iridomyrmecin and (-)-Isoiridomyrmecin, Major Components of Matatabilactone, Nat. Prod. Commun, 11 , 883-886, 2016.
97.
Nakazaki, A.; Mori, A.; Kobayashi, S.; Nishikawa, T. A Divergent Approach to the Diastereoselective Synthesis of 3,3-Disubstituted Oxindoles from Atropisomeric N-Aryl Oxindole Derivatives., Chem. Asian J, 11, 3267-3274, 2016. DOI: 10.1002/asia.201601183
96. Ueno, S.; Nakazaki, A.; Nishikawa, T. A Synthetic Strategy for Saxitoxin Skeleton by a Cascade Bromocyclization: Total Synthesis of (+)-Decarbamoyl-α-saxitoxinol.Org. Lett., 18, 6368-6371, 2016. DOI: 10.1021/acs.orglett.6b03262
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