Masakazu Nambo, Taeko Nishiwaki-Ohkawa, Akihiro Ito, Zachary T. Ariki, Yuka Ito, Yuuki Kato, Muhammad Yar, Jacky C. -H. Yim, Emily Kim, Elizabeth Sharkey, Keiko Kano, Emi Mishiro-Sato, Kosuke Okimura, Michiyo Maruyama, Wataru Ota, Yuko Furukawa, Tomoya Nakayama, Misato Kobayashi, Fumihiko Horio, Ayato Sato, Cathleen M. Crudden, Takashi Yoshimura. Synthesis and preclinical testing of a selective beta-subtype agonist of thyroid hormone receptor ZTA-261. Commun Med4, 152 (2024).
Tomoya Nakayama, Miki Tanikawa, Yuki Okushi, Thoma Itoh, Tsuyoshi Shimmura, Michiyo Maruyama, Taiki Yamaguchi, Akiko Matsumiya, Ai Shinomiya, Ying-Jey Guh, Junfeng Chen, Kiyoshi Naruse, Hiroshi Kudoh, Yohei Kondo, Honda Naoki, Kazuhiro Aoki, Atsushi J. Nagano, Takashi Yoshimura. A transcriptional program underlying the circannual rhythms of gonadal development in medaka. Proceedings of the National Academy of Sciences of the United States of America 120(52), e2313514120 (2023).
Apirada Padlom, Daisuke Ono, Rio Hamashima, Yuko Furukawa, Takashi Yoshimura, Taeko Nishiwaki-Ohkawa. Level of constitutively expressed BMAL1 affects the robustness of circadian oscillations. Sci Rep12, 19519 (2022).
Nakayama T, Okimura K, Shen J, Guh YJ, Tamai TK, Shimada A, Minou S, Okushi Y, Shimmura T, Furukawa Y, Kadofusa N, Sato A, Nishimura T, Tanaka M, Nakayama K, Shiina N, Yamamoto N, Loudon AS, Nishiwaki-Ohkawa T, Shinomiya A, Nabeshima T, Nakane Y, Yoshimura T.
Seasonal changes in NRF2 antioxidant pathway regulates winter depression-like behavior. Proceedings of the National Academy of Sciences of the United States of America [Epub ahead of print] (2020).
Nakayama T, Shimmura T, Shinomiya A, Okimura K, Takehana Y, Furukawa Y, Shimo T, Senga T, Nakatsukasa M, Nishimura T, Tanaka M, Okubo K, Kamei Y, Naruse K, Yoshimura T.
Seasonal regulation of the lncRNA LDAIR modulates self-protective behaviours during the breeding season. Nature Ecology & Evolution [Epub ahead of print] (2019).
Featured in BEHIND THE PAPER
Tamai TK, Nakane Y, Ota W, Kobayashi A, Ishiguro M, Kadofusa N, Ikegami K, Yagita K, Shigeyoshi Y, Sudo M, Nishiwaki-Ohkawa T, Sato A, Yoshimura T.
Identification of circadian clock modulators from existing drugs. EMBO Molecular Medicine e8724 (2018).
Shimmura T, Nakayama T, Shinomiya A, Fukamachi S, Yasugi M, Watanabe E, Shimo T, Senga T, Nishimura T, Tanaka M, Kamei Y, Naruse K, YoshimuraT.
Dynamic plasticity in phototransduction regulates seasonal changes in color perception. Nature Communications 8, 412 (2017).
Maeda R, Shimo T, Nakane Y, Nakao N, Yoshimura T.
Ontogeny of the Saccus Vasculosus, a Seasonal Sensor in Fish. Endocrinology 156, 4238-43 (2015)
Shimmura T, Ohashi S, Yoshimura T.
The highest-ranking rooster has priority to announce the break of dawn. Scientific Reports 5, 11683 (2015)
Oshima T, Yamanaka I, Kumar A, Yamaguchi J, Nishiwaki-Ohkawa T, Muto K, Kawamura R, Hirota T, Yagita K, Irle S, Kay SA, Yoshimura T, Itami K.
C-H activation generates period-shortening molecules that target cryptochrome in the mammalian circadian clock. Angewandte Chemie International Edition in English 54, 7193-7 (2015)
Ikegami K, Liao XH, Hoshino Y, Ono H, Ota W, Ito Y, Nishiwaki-Ohkawa T, Sato C, Kitajima K, Iigo M, Shigeyoshi Y, Yamada M, Murata Y, Refetoff S, Yoshimura T.
Tissue-specific post-translational modification allows functional targeting of thyrotropin Cell Reports 9, 1-9 (2014) Selected for cover picture
Nakane Y, Ikegami K, Iigo M, Ono H, Takeda K, Takahashi D, Uesaka M, Kimijima M, Hashimoto R, Arai N, Suga T, Kosuge K, Abe T, Maeda R, Senga T, Amiya N, Azuma T,
Amano M, Abe H, Yamamoto N, Yoshimura T.
The saccus vasculosus of fish is a sensor of seasonal changes in day length. Nature Communications 4, 2108 (2013) Featured article in Nature Communications, Nature Japan「注目のハイライト」
Tomida S, Mamiya T, Sakamaki H, Miura M, Aosaki T, Masuda M, Niwa M, Kameyama T, Kobayashi J, Iwaki Y, Imai S, Ishikawa A, Abe K, Yoshimura T, Nabeshima T, Ebihara S.
Identification of Usp46, encoding a ubiquitin specific peptidase, as a quantitative trait gene regulating mouse immobile behavior in the tail suspension test and forced swimming test. Nature Genetics 41, 688-695 (2009)
Nishiwaki T, Satomi Y, Kitayama Y, Terauchi K, Kiyohara R, Takao T, Kondo T.
A sequential program of dual phosphorylation of KaiC as a basis for circadian rhythm in cyanobacteria. EMBO J 26, 4029-4037 (2007)
Nakao N, Ono H, Yamamura T, Anraku T, Takagi T, Higashi K, Yasuo S, Katou Y, Kageyama S, Uno Y, Kasukawa T, Iigo M, Sharp PJ, Iwasawa A, Suzuki Y, Sugano S, Niimi T, Mizutani M, Namikawa T, Ebihara S, Ueda HR, Yoshimura T.
Thyrotrophin in the pars tuberalis triggers photoperiodic response. Nature 452, 317-322 (2008) News & Views, Faculty of 1000 Biology “Exceptional”
Yoshimura T, Yasuo S, Watanabe M, Iigo M, Yamamura T, Hirunagi K, Ebihara S.
Light-induced hormone conversion of T4 to T3 regulates photoperiodic response of gonads in birds. Nature 426, 178-181 (2003)
