原著論文(2000年以降)

2000

Immunocytochemical Localization of a Neuron-specific Thrombospondin-1-like Protein, NELL2: Light and Electron Microscopic Studies in the Rat Brain.
Oyasu, M., Kuroda, S., Nakashita, M., Fujimiya, M., Kikkawa, U., and Saito, N.
Brain Res. Mol. Brain Res. 76 (2000), 151-160.


ENH, Containing PDZ and LIM Domain, Heart/Skeletal Muscle-specific Protein, Associates with Cytoskeletal Proteins through the PDZ Domain.
Nakagawa, N., Hoshijima, M., Oyasu, M., Saito, N., Tanizawa, K., and Kuroda, S.
Biochem. Biophys. Res. Commun. 272 (2000), 505-512.


Identification of CRAM, a Novel unc-33 Gene Family Protein That Associates with CRMP3 and Protein-tyrosine Kinase(s) in the Developing Rat Brain.
Inatome, R., Tsujimura, T., Hitomi, T., Mitsui, N., Hermann, P., Kuroda, S., Yamamura, H., and Yanagi, S.
J. Biol. Chem. 275 (2000), 27291-27302.


Identification and Characterization of PRKCBP1, a Candidate RACK-like Protein.
Fossey, S. C., Kuroda, S., Price, J. A., Pendleton, J. C., Freedman, B. I., and Bowden, D. W.
Mam. Genome 11 (2000), 919-925.


Molecular Cloning and Heterologous Expression of Pea Seedling Copper Amine Oxidase.
Koyanagi, T., Matsumura, K., Kuroda, S., and Tanizawa, K.
Biosci. Biotechnol. Biochem. 64 (2000) 717-722.


2001

The Covalent Structure of the Small Subunit from Pseudomonas putida Amine Dehydrogenase Reveals the Presence of Three Novel Types of Internal Cross-linkages, All Involving Cysteine in a Thio-ether Bond.
Vandenberghe, I., Kim, J.-K., Devreese, B., Hacisalihoglu, A., Iwabuki, H., Okajima, T., Kuroda, S., Adachi, O., Jongejan, J. A., Duine, J. A., Tanizawa, K., and Van Beeumen, J.
J. Biol. Chem. 276 (2001) 42923-42931.


Structure of a Quinohemoprotein Amine Dehydrogenase with an Uncommon Redox Cofactor and Highly Unusual Crosslinking.
Datta, S., Mori, Y., Takagi, K., Kawaguchi, K., Chen, Z.-W., Okajima, T., Kuroda, S., Ikeda, T., Kano, K., Tanizawa, K., and Mathews, F. S.
Proc. Natl. Acad. Sci. U. S. A. 98 (2001) 14268-14273.


Sharpin, a Novel Postsynaptic Density Protein that Directly Interacts with the Shank Family of Proteins.
Lim, S., Sala, C., Yoon, J., Park, S., Kuroda, S., Sheng, M., and Kim, E.
Mol. Cell. Neurosci. 17 (2001), 385-397.


Physicochemical and Immunological Characterization of Hepatitis B Virus Envelope Particles Exclusively Consisting of the Entire L (Pre-S1+Pre-S2+S) Protein.
Yamada, T., Iwabuki, H., Kanno, T., Tanaka, H., Kawai, T., Fukuda, H., Kondo, A., Seno, M., Tanizawa, K., and Kuroda, S.
Vaccine 19 (2001), 3154-3163.


Identification of Novel Membrane-bound Phospholipase D from Streptoverticillium cinnamoneum, Possessing Only Hydrolytic Activity.
Ogino, C., Negi, Y., Daido, H., Kanemasu, M., Kondo, A., Kuroda, S., Tanizawa, T., Shimizu, N., and Fukuda, H.
Biochem. Biophys. Acta 1530 (2001) 23-31.


Brain-Specific Human Genes, NELL1 and NELL2, are Predominantly Expressed in Neuroblastoma and Other Embryonal Neuroepithelial Tumors
Maeda, K., Matsuhashi, S., Tabuchi, K., Watanabe, T., Katagiri, T., Oyasu, M., Saito, N., and Kuroda, S.
Neurol. Med. Chir. (Tokyo) 41 (2001), 582-589.
    

2002

Craniosynostosis in Transgenic Mice Overexpressing Nell-1.
Zhang, X., Kuroda, S., Carpenter, D., Nishimura, I., Soo, C., Moats, R., Iida, K., Wisner, E., Hu, F.-Y., Miao, S., Beanes, S., Dang, C., Vastardis, H., Longaker, M., Tanizawa, K., Kanayama, N., Saito, N., and Ting, K.
J. Clin. Invest. 110 (2002), 861-870.


Size Distribution Measurement of Vesicles by Atomic Force Microscopy.
Kanno, T., Yamada, T., Iwabuki, H., Tanaka, H., Kuroda, S., Tanizawa, K., and Kawai, T.
Anal. Biochem. 309 (2002), 196-199.


Crystal Structure of Quinohemoprotein Amine Dehydrogenase from Pseudomonas putida.
Identification of a Novel Quinone Cofactor Encaged by Multiple Thio-ether Cross-bridges.
Satoh, A., Kim, J.-K., Miyahara, I., Devreese, B., Vandenberghe, I., Hacisalihoglu, A., Okajima, T., Kuroda, S., Adachi, O., Duine, J. A., Van Beeumen, J., Tanizawa, K., and Hirotsu, K.
J. Biol. Chem. 277 (2002) 2830-2834.


A brain-specific EGF-like family protein, NELL2, is a novel survival factor for neurons.
Aihara, K., Horie, M., Tanizawa, K., and Kuroda, S.
Neurobiology of Aging 23 (2002) S352.


2003

Role of Copper Ion in Bacterial Copper Amine Oxidase: Spectroscopic and Crystallographic Studies of Metal-substituted Enzymes.
Kishishita, S., Okajima, T., Kim, M., Yamaguchi, H., Hirota, S., Suzuki, S., Kuroda, S., Tanizawa, K., and Mure, M.
J. Am. Chem. Soc. 125 (2003) 1041-1055.


A PKC?-ENH-channel Complex Modulates N-type Ca2+ Channels.
Maeno-Hikichi Y., Chang, S., Matsumura, K., Lai, M., Lin, H., Nakagawa, N., Kuroda, S., and Zhang, J. F.
Nature Neuroscience 6 (2003), 468-475.


Nanoparticles for the Delivery of Genes and Drugs to Human Hepatocytes.
Yamada, T., Iwasaki, Y., Tada, H., Iwabuki, H., Chuah, M. K. L., VandenDriessche, T., Fukuda, H., Kondo, A., Ueda, M., Seno, M., Tanizawa, K., and Kuroda, S.
Nature Biotechnology 21 (2003) 885-890.


Disrupted-in-Schizophrenia 1, a Candidate Gene for Schizophrenia, Participates in Axonal Outgrowth.
Miyoshi, K., Honda, A., Baba, K., Taniguchi, M., Oono, K., Fujita, T., Kuroda, S., Katayama, T., and Tohyama, M.
Mol. Psychiatry 8 (2003) 685-694.


Overexpression of Nell-1, a Craniosynostosis Associated Gene, Induces Apoptosis in Osteoblasts during Craniofacial Development.
Zhang, X., Carpenter, D., Bokui, N., Soo, C., Miao, S., Truong, T., Wu, B., Chen, I., Vastardis, H., Tanizawa, K., Kuroda, S., and Ting, K.
J. Bone Mineral Res. 18 (2003) 2126-2134.


A Neuron-specific EGF Family Protein, NELL2, Promotes Survival of Neurons through Mitogen-activated Protein Kinases.
Aihara, K., Kuroda, S., Kanayama, N., Matsuyama, S., Tanizawa, K., and Horie, K.
Brain Res. Mol. Brain Res. 116 (2003) 86-93.


Detection of Protein-Protein Interactions on SiO2/Si Surfaces by Spectroscopic Ellipsometry.
Kodera, S., Okajima, T., Iwabuki, H., Kitaguchi, D., Kuroda, S., Yoshinobu, T., Tanizawa,, K., Futai, M., and Iwasaki, H.
Anal. Biochem., 321 (2003) 65-70.


Phospholipase D from Streptoverticillium cinnamoneum: Protein Engineering and Application for Phospholipid Production.
Ogino, C., Kuroda, S., Tokuyama, S., Kondo, A., Shimizu, N., Tanizawa, K., and Fukuda, H.
J. Mol. Cat. B 2-6 (2003) 107-115.


2004

Expression of Fasciculation and Elongation Protein Zeta-1 (FEZ1) in the Developing Rat Brain.
Honda, A., Miyoshi, K., Baba, K., Taniguchi, M., Koyama, Y., Kuroda, S., Katayama, T., and Tohyama, M.
Brain Res. Mol. Brain Res. 122 (2004) 89-92.


Enhanced Long-term Potentiation In Vivo in the Dentate Gyrus of Mice Lacking a Neuron-specific EGF Family Protein, NELL2.
Matsuyama, S., Aiharam K., Nishino, N., Takeda, S., Tanizawa, K., Kuroda, S., and Horie, M.
Neuroreport 15 (2004) 417-420.


Identification of a Tissue-non-specific Homologue of Axonal Fasciculation and Elongation Protein Zeta-1 (FEZ1).
Fujita, T., Ikuta, J., Hamada, J., Okajima, T., Tatematsu, K., Tanizawa, K., and Kuroda, S.
Biochem. Biophys. Res. Commun. 313 (2004) 738-744.


Chemical Rescue of a Site-specific Mutant of Bacterial Copper Amine Oxidase for Generation of the Topa Quinone Cofactor.
Matsunami, H., Okajima, T., Hirota, S., Yamaguchi, H., Hori, H., Kuroda, S., and Tanizawa, K.
Biochemistry 43(2004) 2178-2187.


Over-expression System for Secretory Phospholipase D by Streptomyces lividans.
Ogino, C., Kanemasu, M., Hayashi, Y., Shimizu, N., Kondo, A., Tokuyama, S., Tahara, Y., Kuroda, S., Tanizawa, K, and Fukuda, H.
Appl. Microbiol. Biotechnol. 64 (2004) 823-828.


Novel Tissue and Cell Type-specific Gene Delivery System Using Surface Engineered Hepatitis B Virus Nanoprotein Particles.
Yamada, T., Kondo, A., Ueda, M., Seno, M., Tanizawa, K., and Kuroda, S.
Current Drug Targets: Infectious Disorders 4 (2004), No. 2, 163-167.


2005

PKCε-PKD1 Signaling Complex at Z-discs Plays a Pivotal Role in the Cardiac Hypertrophy Induced by G-protein Coupling Receptor Agonists.
Iwata, M., Maturana, A., Hoshijima, M., Tatematsu, K., Okajima, T., Vandenheede, J. R., Van Lint, J., Tanizawa, K., and Kuroda, S.
Biochem. Biophys. Res. Commun. 327 (2005) 1105-1113.


Nuclear-Cytoplasmic Shuttling of a RING-IBR Protein RBCK1 and Its Functional Interaction with Nuclear Body Proteins.
Tatematsu, K., Yoshimoto, N., Koyanagi, T., Tokunaga, C., Tachibana, T., Yoneda, Y., Yoshida, M., Okajima, T., Tanizawa, K., and Kuroda, S.
J. Biol. Chem. 280 (2005) 22937-22944.


Identification of FEZ1 as a Protein That Interacts with JC Virus Agnoprotein and Microtubules: Role of Agnoprotein-Induced Dissociation of FEZ1 from Microtubules in Viral Propagation.
Suzuki, T., Okada, Y., Semba, S., Orba, S., Yamanouchi, S., Endo, S., Tanaka, S., Fujita, T., Kuroda, S., Nagashima, K., and Sawa, H.
J. Biol. Chem. 280 (2005) 24948-24956.


Spatial Learning of Mice Lacking a Neuron-Specific EGF Family Protein, NELL2.
Matsuyama, S., Doe, N., Kurihara, N., Tanizawa, K., Kuroda, S., Iso, H., and Horie, M.
J. Pharmacol. Sci. 98 (2005) 239-243.


The Specific Delivery of Proteins to Human Liver Cells by Engineered Bio-Nanocapsules.
Yu, D., Amano, C., Fukuda, T., Yamada, T., Kuroda, S., Tanizawa, K., Kondo, A., Ueda, M., Yamada, H., Tada, H., and Seno, M.
FEBS J. 272 (2005) 3651-3660.


Cytoplasmic Tethering of a RING Protein RBCK1 by Its Splice Variant Lacking the RING Domain.
Yoshimoto, N., Tatematsu, K., Koyanagi, T., Okajima, T., Tanizawa, K., and Kuroda, S.
Biochem. Biophys. Res. Commun. 335 (2005) 550-557.


Re-investigation of Metal ion Specificity for Quinine Cofactor Biogenesis in Bacterial Copper Amine Oxidase
Okajima, T., Kishishita, S., Chiu, Y.-C., Murakawa, T., Kim, M., Yamaguchi, H., Hirota, S., Kuroda, S., and Tanizawa, K.
Biochemistry 44 (2005) 12041-12048.


2006

NELL-1 Induced Bone Formation within the Distracted Intermaxillary Suture.
Cowan, C. M., Cheng, S., Ting, K., Soo, C., Walder, B., Wu, B., Kuroda, S., and Zhang, X.
Bone 38 (2006) 48-58.


Kinetic and Structural Studies on the Catalytic Role of the Aspartic Acid Residue Conserved in Copper Amine Oxidase
Chiu, Y.-C., Okajima, T., Murakawa, T., Uchida, M., Taki, M., Hirota, S., Kim, M., Yamaguchi, H., Kawano,Y., Kamiya, N., Kuroda, S., Hayashi, H., Yamamoto, Y., and Tanizawa, T.
Biochemistry 45 (2006) 4105-4120.


Quantum Mechanical Hydrogen Tunneling in Bacterial Copper Amine Oxidase Reaction
Murakawa, T., Okajima, T., Kuroda, S., Nakamoto, T., Taki, M., Yamamoto, Y., Hayashi, H., and Tanizawa, K.
Biochem. Biophys. Res. Commun. 342 (2006) 414-423.


Involvement of a Putative [Fe-S]-cluster-binding Protein in the Biogenesis of Quinohemoprotein Amine Dehydrogenase
Ono, K., Okajima, T., Tani, M., Kuroda, S., Sun, D., Davidson, V. L., and Tanizawa, K.
J. Biol. Chem. 281 (2006) 13672-84.


Secretory production system of bionanocapsules using a stably transfected insect cell line
Shishido, T., Muraoka, M., Ueda, M., Seno, M., Tanizawa, K., Kuroda, S., Fukuda, H., and Kondo. A.
Appl. Microbial. Biotechnol. 73 (2006) 505-511.


Quantitative and Dynamic Analyses of G Protein-Coupled Receptor Signaling in Yeast Using Fus1, Enhanced Green Fluorescence Protein (EGFP), and His3 Fusion Protein
Ishii, J., Matsumura, S., Kimura, S., Tatematsu, K., Kuroda, S., Fukuda, H., and Kondo, A.
Biotechnol. Prog. 22 (2006) 954-960.


Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development.
Zhang, X., Cowan, C. M., Jiang, X., Soo, C., Miao, S., Carpenter, D., Wu, B., Kuroda, S., and Ting, K.
Lab Invest. 86 (2006) 633-44.


Nell-1-induced bone regeneration in calvarial defects.
Aghaloo, T., Cowan, C. M., Chou, Y. F., Zhang, X., Lee, H., Miao, S., Hong, N., Kuroda, S., Wu, B., Ting, K., and Soo, C.
Am. J. Pathol. 169 (2006) 903-15.


2007

Gene Therapy of Liver Tumors with Human Liver-Specific Nanoparticles.
Iwasaki, Y., Ueda, M., Yamada, T., Kondo, A., Seno, M., Tanizawa, K., Kuroda, S., Sakamoto, M., and Kitajima, M.
Cancer Gene Ther. 14 (2007) 74-81.
    

A cold-active and thermostable alcohol dehydrogenase of a psychrotorelant from Antarctic seawater, Flavobacterium frigidimaris KUC-1.
Kazuoka, T., Oikawa, T., Muraoka, I., Kuroda, S., and Soda K.
Extremophiles 11 (2007) 257-267.


Fasciculation and elongation protein zeta-1 (FEZ1) participates in the polarization of hippocampal neuron by controlling the mitochondrial motility.
Ikuta, J., Maturana, A., Fujita, T., Okajima, T., Tatematsu, K., Tanizawa, K., and Kuroda, S.
Biochem. Biophys. Res. Commun. 353 (2007) 127-132.


Characterization of Bio-Nanocapsule as a Transfer Vector Targeting Human Hepatocyte Carcinoma by Disulfide Linkage Modification.
Nagaoka, T., Fukuda, T., Yoshida, S., Yu, D., Kuroda, S., Tanizawa, K., Kondo, A., Ueda, M., Yamada, H., Tada, H., and Seno, M.
J Control Release 118 (2007) 348-356.


Synergistic Effects of Nell-1 and BMP-2 on the Osteogenic Differentiation of Myoblasts.
Cowan CM, Jiang X, Hsu T, Soo C, Zhang B, Wang JZ, Kuroda S, Wu B, Zhang Z, Zhang X, Ting K.
J Bone Miner Res. 22 (2007) 918-930.


Axonal Guidance Protein FEZ1 Associates with Tubulin and Kinesin Motor Protein to Transport Mitochondria in Neurites of NGF-Stimulated PC12 Cells.
Fujita T, Maturana AD, Ikuta J, Hamada J, Walchli S, Suzuki T, Sawa H, Wooten MW, Okajima T, Tatematsu K, Tanizawa K, Kuroda S.
Biochem Biophys Res Commun. 361 (2007) 605-610.

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Gene Therapy of Liver Tumors with Human Liver-Specific Nanoparticles.
Ueda M, Iwasaki Y, Yamada T, Kondo A, Seno M, Tanizawa K, Kuroda S, Sakamoto M, and Kitajima M.
Cancer Gene Ther. 14 (2007) 440.


2008

The MAP Kinase p38 Links Shiga Toxin Dependent Signaling and Trafficking.
Walchli S, Skanland SS, Gregers TF, Lauvrak SU, Torgersen ML, Ying M, Kuroda S, Maturana A, Sandvig K.
Mol Biol Cell 19 (2008) 95-104.


Involvement of MAPK signaling molecules and Runx2 in the NELL1-induced osteoblastic differentiation.
Bokui N, Otani T, Igarashi K, Kaku J, Oda M, Nagaoka T, Seno M, Tatematsu K, Okajima T, Matsuzaki T, Ting K, Tanizawa K, and Kuroda S.
FEBS Lett. 582 (2008) 365-371.


Bio-nanocapsule Conjugated with Liposomes for In Vivo Pinpoint Delivery of Various Materials.
Jung JH, Matsuzaki T, Tatematsu K, Okajima T, Tanizawa K, and Kuroda S.
J Control Release 126 (2008) 255-264.


Yeast-based fluorescence reporter assay of G protein-coupled receptor signaling for flow cytometric screening: FAR1-disruption recovers loss of episomal plasmid caused by signaling in yeast.
Ishii J, Tanaka T, Matsumura S, Tatematsu K, Kuroda S, Ogino C, Fukuda H. and Kondo A.
J Biochem. (Tokyo) 143 (2008) 667-674.


Identification of Ubiquitin Ligase Activity of RBCK1 and Its Inhibition by Splice Variant RBCK2 and Protein Kinase Cβ?
Tatematsu K, Yoshimoto N, Okajima T, Tanizawa K, and Kuroda S.
J Biol Chem. 283 (2008) 11575-11585.


Enigma homolog 1 scaffolds protein kinase D1 to regulate the activity of the cardiac L-type voltage-gated calcium channel.
Maturana AD, Walchli S, Iwata M, Ryser S, Van Lint J, Hoshijima M, Schlegel W, Ikeda Y, Tanizawa K, and Kuroda S.
Caridiovascular Res. 78 (2008) 458-465.


Crystal structures of Lymnaea stagnalis AChBP in complex with neonicotinoid insecticides imidacloprid and clothianidin.
Ihara M, Okajima T, Yamashita A, Oda T, Hirata K, Nishiwaki H, Morimoto T, Akamatsu M, Ashikawa Y, Kuroda S, Mega R, Kuramitsu S, Sattelle DB, and Matsuda K.
Invert Neurosci. 8 (2008) 71-81.


In Vivo Protein Delivery to Human Liver-derived Cells Using Hepatitis B Virus Envelope Pre-S Region.
Kasuya T, Yamada T, Uyeda A, Matsuzaki T, Okajima T, Tatematsu K, Tanizawa K, and Kuroda S
J Biosci Bioeng. 106 (2008) 99-102.


In Vivo Delivery of Bio-nanocapsules Displaying L4-PHA Isolectin to Malignant Tumors Overexpressing N-Acetylglucosaminyltransferase V
Kasuya T, Jung JH, Kadoya H, Matsuzaki T, Tatematsu K, Okajima T, Miyoshi E, Tanizawa K, and Kuroda S
Human Gene Therapy 19 (2008) 887-895.


Expression of Squamous Cell Carcinoma Antigen-1 in Liver Enhances the Uptake of HBV Envelope-derived Bio-nanocapsules in Transgenic Rats
Kasuya T, Nomura S, Matsuzaki T, Jung J, Yamada T, Tatematsu K, Okajima T, Tanizawa K, and Kuroda S
FEBS J 275 (2008) 5714-5724.


2009

Role of the T-type Calcium Channel Cav3.2 in the Chronotropic Action of Corticosteroids in Isolated Rat Ventricular Myocytes
Maturana A, Lenglet S, Python M, Kuroda S, and Rossier M F
Endocrinology 150 (2009) 3726-3734.


Human eosinophil cationic protein enhances stress fiber formation in Balb/c 3T3 fibroblasts and differentiation of rat neonatal cardiomyocytes
Fukuda T, Iwata M, Kitazoe M, Maeda T, Salomon D, Hirohata S, Tanizawa K, Kuroda S, and Seno M
Growth Factors 27 (2009) 228-236.


Accumulation of polyubiquitinated proteins by overexpression of RBCC protein interacting with protein kinase C2, a splice variant of ubiquitin ligase RBCC protein interacting with protein kinase C1
Yoshimoto N, Tatematsu K, Okajima T, Tanizawa K, and Kuroda S.
FEBS J 276 (2009) 6375-6385


2010

Bio-nanocapsule-based enzyme-antibody conjugates for ELISA
Iijima M, Matsuzaki T, Kadoya H, Hatahira S, Hiramatsu S, Jung G, Tanizawa K, and Kuroda S.
Anal Biochem 396 (2010) 257-261


Splice variants of Enigma Homolog, differentially expressed during heart development, promote or prevent hypertrophy.
Yamazaki T., Walchli S., Fujita T., Ryser S., Hoshijima M., Schlegel W., Kuroda S., and Maturana A.D.
Cardiovascular Research 86 (2010) 374-382.


Hepatoma-targeted gene delivery using a tumor cell-specific gene regulation system combined with a human liver cell-specific bionanocapsule.
Kang JH, Oishi J, Kim JH, Ijuin M, Toita R, Jun B, Asai D, Mori T, Niidome T, Tanizawa K, Kuroda S, and Katayama Y.
Nanomedicine 6 (2010) 583-589.


A gene delivery system specific for hepatoma cells and an intracellular kinase signal based on human liver-specific bionanocapsules and signal-responsive artificial polymer.
Oishi J, Jung J, Tsuchiya A, Toita R, Kang JH, Mori T, Niidome T, Tanizawa K, Kuroda S, and Katayama Y.
Int J Pharm. 396 (2010) 174-178.


Construction of protein-modified TiO2 nanoparticles for use with ultrasound irradiation in a novel cell-injuring method.
Ogino C., Shibata N., Sasai R., Takaki K., Miyachi Y., Kuroda S., Ninomiya K., and Shimizu N.
Bioorganic & Medicinal Chemistry Letters 20 (2010) 5320-5325.


2011

Nell-1, a key functional mediator of Runx2, partially rescues calvarial defects in Runx2(+/-) mice.
Zhang X, Ting K, Bessette CM, Culiat CT, Sung SJ, Lee H, Chen F, Shen J, Wang JJ, Kuroda S, and Soo C.
J Bone Miner Res. 26 (2011) 777-791.


Nanocapsules Incorporating IgG Fc-binding Domain Derived from Staphylococcus aureus Protein-A for Displaying IgGs on Immunosensor Chips
Iijima M, Kadoya H, Matsuzaki T, Hatahira S, Hiramatsu S, Jung G, Martin A, Quinn J, Jung J, Jeong SY, Choi EK, Arakawa T, Hinako F, Kusunoki M, Yoshimoto N, Niimi T, Tanizawa K, and Kuroda S.
Biomaterials 32 (2011) 1455-1464


Human Liver Specific Nano-Carrier in a Novel Mouse Xenograft Model Bearing Non-Cancerous Human Liver Tissue
Matsuura Y, Yagi H, Matsuda S, Itano O, Koichi A, Kuroda S, Ueda M, and Kitagawa Y
European Surgical Research 46 (2011) 65-72.


LIM Domains Regulate Protein Kinase C Activity: A Novel Molecular Function
Maturana A. D., Nakagawa N., Yoshimoto N., Tatematsu K., Hoshijima M., Tanizawa K., and Kuroda S.
Cell Signaling 23 (2011) 928-934.


Efficient and rapid purification of drug- and gene-carrying bio-nanocapsules, hepatitis B virus surface antigen L particles, from Saccharomyces cerevisiae
Jung J., Iijima M., Yoshimoto N., Sasaki M., Niimi T., Tatematsu K., Jeong S.Y., Choi E.K., Tanizawa K., and Kuroda S.
Protein Exp. Purif. 78 (2011) 149-155.


Efficient Production and Characterization of Recombinant Human NELL1 Protein in Human Embryonic Kidney 293-F Cells.
Hasebe A, Tashima H, Ide T, Iijima M, Yoshimoto N, Ting K, Kuroda S, Niimi T.
Mol Biotechnol. 2011 Aug 5. [Epub ahead of print]


Fluorophore-labeled nanocapsules displaying IgG Fc-binding domains for the simultaneous detection of multiple antigens.
Iijima M, Matsuzaki T, Yoshimoto N, Niimi T, Tanizawa K, and Kuroda S.
Biomaterials 32 (2011) 9011-9020.


2012

Targeted sonodynamic therapy using protein-modified TiO2 nanoparticles.
Ninomiya, K., Ogino, C., Oshima, S., Sonoke, S., Kuroda, S., and Shimizu, N.
Ultrasonics Sonochemistry 19 (2012) 607-614.

An Unusual Subtilisin-like Serine Protease is Essential for Biogenesis of Quinohemoprotein Amine Dehydrogenase.
Nakai, T., Ono, K., Kuroda, S., Tanizawa, K., and Okajima, T.
J. Biol. Chem. 287 (2012) 6530-6538

Hepatitis B Virus Envelope L Protein-Derived Bio-Nanocapsules: Mechanisms of Cellular Attachment and Entry into Human Hepatic Cells.
Yamada, M., Oeda A., Jung J.H., Iijima M., Yoshimoto, N., Niimi, T., Jeong, S.Y., Choi, E.K., Tanizawa, K., and Kuroda, S.
J. Controlled Release 160 (2012) 322?329.

The role of PKC isoforms in the inhibition of NF-κB activation by vitamin K2 in human hepatocellular carcinoma cells.
Xia, J., Matsuhashi, S., Hamajima, H., Iwane, S., Takahashi, H., Eguchi, Y., Mizuta, T., Fujimoto, K., Kuroda, S., and Ozaki, I.
J. Nutr. Biochem. 23 (2012) 1668-1675.

Cell wall trapping of autocrine 1 peptides for human G-protein-coupled receptors on the yeast cell surface Ishii, J., Yoshimoto, N., Tatematsu, K., Kuroda, S., Ogino, C., Fukuda, H., and Kondo, A.
PLoS ONE 7 (2012) e37136.

Targeting of Polyplex to Human Hepatic Cells by Bio-nanocapsules, Hepatitis B Virus Surface Antigen L Protein Particles Somiya, M., Yoshimoto, N., Iijima, M., Niimi, T., Dewa, T., Jung, J., and Kuroda, S.
Bioorg. Med. Chem. 20 (2012) 3873-3879.

Engineered bio-nanocapsules, hepatitis B virus surface antigen L protein particles, for in vivo active targeting to splenic dendritic cells Matsuo, M., Yoshimoto, N., Iijima, M., Niimi, T., Jung, J., Jeong, S. Y., Choi, E. K., Sewaki, T., Arakawa, T., and Kuroda, S.
Int. J. Nanomed. 7 (2012) 3341-3350.

The C-terminal region of NELL1 mediates osteoblastic cell adhesion through integrin a3b1 Hasebe, A., Nakamura, Y., Tashima, T., Takahashia, K., Iijima, M., Yoshimoto, N., Ting, K., Kuroda, S., and Niimi, T.
FEBS Letters 586 (2012) 2500-2506.

NELL-1 promotes cell adhesion and differentiation via Integrinβ1.
Shen J, James AW, Chung J, Lee K, Zhang JB, Ho S, Lee KS, Kim TM, Niimi T, Kuroda S, Ting K, Soo C.
J Cell Biochem. 113 (2012) 3620-3628.

Nano-visualization of oriented-immobilized IgGs on immunosensors by high-speed atomic force microscopy Iijima, M., Somiya, M., Yoshimoto, N., Niimi, T., and Kuroda, S.
Scientific Reports 2 (2012) 790 (5 pages).


2013

An automated system for high-throughput single cell-based breeding Nobuo Yoshimoto, Akiko Kida, Xu Jie, Masaya Kurokawa, Masumi Iijima, Tomoaki Niimi, Andres D. Maturana, Itoshi Nikaido, Hiroki R. Ueda, Kenji Tatematsu, Katsuyuki Tanizawa, Akihiko Kondo, Ikuo Fujii & Shun’ichi Kuroda Scientific Reports 3 (2013) 1191 (9 pages).

Bio-nanocapsules for signal enhancement of alkaline phosphatase-linked immunosorbent assays Masumi IIJIMA, Mikako YAMAMOTO, Nobuo YOSHIMOTO, Tomoaki NIIMI, and Shun’ichi KURODA Bioscience, Biotechnology, and Biochemistry in press (2013)

Cell surface-fluorescence immunosorbent assay for real-time detection of hybridomas with efficient antibody secretion at the single-cell level Akiko Kida, Masumi Iijima, Tomoaki Niimi, Andres D. Maturana, Nobuo Yoshimoto*, and Shun’ichi Kuroda* Anal Chem 85 (2013) 1753-1759

A bio-nanocapsule containing envelope (E) protein domain III of Japanese encephalitis virus (JEV) protects mice against lethal JEV infection Takeshi Miyata, Senji Tafuku, Tetsuya Harakuni, Masayuki Tadano, Nobuo Yoshimoto, Masumi Iijima, Hidenori Matsuo, Shun’ichi Kuroda, and Takeshi Arakawa
Microbiol. Immunol. In press (2013)

DHEA Prevents Mineralo- and Glucocorticoid Receptor-Induced Chronotropic and Hypertrophic Actions in Isolated Rat Cardiomyocytes
Tiphaine Mannic, Mounira Mouffok, Magaly Python, Takehisa Yoshida, Andres D. Maturana, Nicolas Vuilleumier, and Michel F. Rossier
Endocrinology, 154, 3, 1271 (2013)


Structural basis for the drug extrusion mechanism by a MATE multidrug transporter
Yoshiki Tanaka, Christopher J. Hipolito, Andrés D. Maturana, KoichiIto, Teruo Kuroda, Takashi Higuchi, Takayuki Katoh, Hideaki E. Kato, 
Motoyuki Hattori, Kaoru Kumazaki, Tomoya Tsukazaki, Ryuichiro Ishitani, Hiroaki Suga & Osamu Nureki
Nature 496, 247–251 (11 April 2013)


Nanocapsule-based Probe for Evaluating the Orientation of Antibodies Immobilized on a Solid Phase
Masumi Iijima, Nobuo Yoshimoto, Tomoaki Niimi, Andrés Daniel Maturana, Shun’ichi Kuroda
Analyst, in press (2013)


Enigma homolog 1 promotes myogenic gene expression and differentiation of C2C12 cells.
Jumpei Ito, Masatoshi Takita, Koichi Takimoto, Andres D. Maturana. Biochem.Biophys.Res.Commun. 435, 483-487 (2013)

Structural basis for the counter-transport mechanism of a H+/Ca2+ exchanger.
Tomohiro Nishizawa, Satomi Kita, Andrés D. Maturana, Noritaka Furuya, Kunio Hirata, Go Kasuya, Satoshi Ogasawara, Naoshi Dohmae, Takahiro Iwamoto, Ryuichiro Ishitani, Osamu Nureki. Science. 341, 168-172 (2013)

High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system
Nobuo Yoshimoto, Kenji Tatematsu, Masumi Iijima, Tomoaki Niimi, Andrés D. Maturana, Ikuo Fujii, Akihiko Kondo, Katsuyuki Tanizawa & Shun’ichi Kuroda
Scientific Reports 4, Article number: 4242 (2013)


2014

Oligomerization-induced Conformational Change in the C-terminal Region of NELL1 Is Necessary for the Efficient Mediation of Murine MC3T3-E1 Cell Adhesion and Spreading
Yoko Nakamura, Ai Hasebe, Kaneyoshi Takahashi, Masumi Iijima, Nobuo Yoshimoto, Andrés D. Maturana, Kang Ting, Shun’ichi Kuroda, and Tomoaki Niimi. Journal of Biological Chemistry, in press (2014)


Specific delivery of microRNA93 into HBV-replicating hepatocytes downregulates protein expression of liver cancer susceptible gene MICA
Motoko Ohno, Motoyuki Otsuka, Takahiro Kishikawa, Chikako Shibata, Takeshi Yoshikawa, Akemi Takata, Ryosuke Muroyama, Norie Kowatari, Masaya Sato, Naoya Kato, Shun’ichi Kuroda and Kazuhiko Koike
Oncotarget. 5(14):5581-90 (2014)

High-throughput de novo screening of receptor agonists with an automated single-cell analysis and isolation system
Nobuo Yoshimoto, Kenji Tatematsu, Masumi Iijima, Tomoaki Niimi, Andrés D. Maturana, Ikuo Fujii, Akihiko Kondo, Katsuyuki Tanizawa and Shun'ichi Kuroda
Sci. Rep. 4, 4242 (2014)

Single-cell-based breeding: Rational strategy for the establishment of cell lines from a single cell with the most favorable properties
Nobuo Yoshimoto and Shun’ichi Kuroda
J Biosci Bioeng. 117(4):394-400 (2014)


Exciton circular dichroism in channelrhodopsin.
Pescitelli G, Kato HE, Oishi S, Ito J, Maturana AD, Nureki O, Woody RW.
J Phys Chem B. 118, 41, 11873-11885 (2014)

2015

A cisplatin‑incorporated liposome that targets the epidermal growth factor receptor enhances radiotherapeutic efficacy without nephrotoxicity
Joohee Jung, Seong‑Yun Jeong, Seok Soon Park, Seol Hwa Shin, Eun Jin Ju, Jinhyang Choi, Jaesook Park, Jae Hee Lee, Inki Kim, Young‑Ah Suh, Jung Jin Hwang, Shun'ichi Kuroda, Jung Shin Lee, Si Yeol Song, and Eun Kyung Choi
Int J Oncol. 46(3):1268-74 (2015)